Search results for " Gametogenesis"

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Lower sperm DNA fragmentation after r-FSH administration in functional hypogonadotropic hypogonadism

2013

Abstract PURPOSE: An observational clinical and molecular study was designed to evaluate the effects of the administration of recombinant human FSH on sperm DNA fragmentation in men with a non-classical form of hypogonadotropic hypogonadism and idiopathic oligoasthenoteratozoospermia. METHODS: In the study were included 53 men with a non-classical form of hypogonadotropic hypogonadism and idiopathic oligoasthenoteratozoospermia. In all patients, sperm DNA fragmentation index (DFI), assessed by terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate (dUTP) in situ DNA nick end-labelling (TUNEL) assay, was evaluated before starting the treatment with 150 IU of recombinant hum…

AdultMaleendocrine systemmedicine.medical_specialtyDNA FragmentationAsthenozoospermialaw.inventionAndrologyHypogonadotropic hypogonadismlawGamete BiologyInternal medicineGeneticsmedicineHumansApoptosis Gametogenesis DNA SpermSettore BIO/06 - Anatomia Comparata E CitologiaGenetics (clinical)GametogenesisSperm Countbusiness.industryHypogonadismObstetrics and GynecologyOligospermiaGeneral Medicinemedicine.diseaseSpermatozoaSpermRecombinant ProteinsEndocrinologyReproductive MedicineAsthenozoospermiaOligospermiaApoptosisRecombinant DNADNA fragmentationFollicle Stimulating Hormone HumanbusinessDevelopmental Biology

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